Daniela Patrício
About
Holds a Bachelor's degree in Biology and a Master'd degree in Molecular and Cellular Biology both from the Department of Biology, University of Aveiro (Aveiro, Potugal). Her master thesis untitled "Implementation of mammalian two-hybrid system for highthroughput drug screening” was developed in the Institute for Biomedicine under the supervision of Doctor Margarida Fardilha and Doctor Ana Sofia Guimarães. Recently, she had a research fellow position in the project “RUNNING away from prostate cancer: WALKING throught the molecular basis of physical activity”, with the reference PTDC/DTP-DES/6077/2014. Currently, she is developing her PhD work in the Fardilha's lab under the supervision of Prof. Margarida Fardilha and Prof. João Mano. Her PhD project, entitled “Organoid technology meets male fertility: an innovative strategy to study and modulate sperm function” aims to develop an in vivo 3D epididymal organoid culture able to mimic the epididymis and blood epididymal barrier (BEB) functions to study the role of this organ on sperm physiology and as a tool for pharmacological testing.
Her research interests comprise high throughput techniques to identify protein-protein interactions related with the male reproductive system.
Publications
Papers:
Patrício D, Fardilha M. The mammalian two-hybrid system as a powerful tool for high-throughput drug screening. Drug Discovery Today. 2020. DOI: 10.1016/j.drudis.2020.01.022
Quintaneiro C, Patrício D, Novais SC, Soares AMVM, Monteiro MS. Endocrine and physiological effects of linuron and S-metolachlor in zebrafish developing embryos. Sci Total Environ. Elsevier B.V.; 2017. DOI: 10.1016/j.scitotenv.2016.11.153
Posters:
Starovlah IM, Radović SM, Patricio D, Kostić TS, Andrić SA. Profile of mitochondrial biogenesis markers and acromosomal reaction are disturbed in spermatozoa from stressed adult rats. CoMBoS - First Congress of Molecular Biologists of Serbia. Abstract book; 2017; p57
Patrício D, Freitas MJ, Guimarães S, Fardilha M. Drug screening using Mammalian Two-Hybrid System. III Post-Graduated Symposium on Biomedicine. Abstract book; 2017.
Patrício D, Guimarães S, Freitas MJ, Fardilha M. Targeting protein-protein interaction using mammalian two-hybrid. SINAL 2017 - 8th Meeting on Signal Transduction - . Abstract book; 2017;42.