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Feb 2, 2022

The Effect of Nutrition on Aging- New article out!

Fardilha's lab just had published a new systematic review that highlights the effect of nutrition on aging! Congratulations to all the...

Feb 2, 2022

May cryopreservation present differentially expressed proteins patterns in human spermatozoa?

A new article is out! Find out more about the most recent work from our group about differentially expressed proteins patterns in the...

Feb 1, 2022

New journal article!

We just published a new article to unravel PCa markers in urine. Urine may be a non-invasive sample with prostatic secretions...

Dec 13, 2021

About our research...

The Portuguese Cancer Research Association (ASPIC) highlighted our paper "Photodynamic therapy of prostate cancer using porphyrnic...

Sep 16, 2021

New paper out!

We published a new paper ! Find out more about Photodynamic therapy in prostate cancer . Find out more in https://doi.org/10.1016/j.jphot...

Aug 12, 2021

New review paper is now available!

Modulation of serine/threonine-protein phosphatase 1 (PP1) complexes: a promising approach in cancer treatment This work rigorously ...

Jun 28, 2021

New Paper Out!

We published a new paper ! Find out more about Protein agregation patterns in breast cancer . Open Access: https://www.mdpi.com/2072-6694...

Jun 1, 2021

What brain and testes have in common? A new article release from our lab tries to figure it out!

An entitled study “Brain and testis: more alike than previously thought?” published in Open Biology, from The Royal Society suggests that...

May 26, 2021

New paper out! Lear more about bovine semen sexing

We published a new paper today! Find out more about bovine semen sexing and what are the sperm membrane proteomics candidates for...

Apr 5, 2021

Juliana Felgueiras completed her PhD

Congratulations to the most recent PhD from our lab! Juliana Felgueiras has defended her PhD thesis untitled "Unraveling the interactome...

Feb 15, 2021

Fighting Bisphenol A-Induced Male Infertility: The Power of Antioxidants

Our new paper on the "Fighting Bisphenol A-Induced Male Infertility: The Power of Antioxidants" is out. Congratulations to all the...

Feb 15, 2021

Disruption of PP1 complexes with the use of bioportides as a novel approach to target sperm motility

Congratulations to the authors for the new paper, an outcome from the 2MOVEorNOT2MOVE project! Find out more https://doi.org/10.1016/j.fe...

Dec 17, 2020

New paper is out!

Our new paper on the "New evidences of ubiquitin–proteasome system activity in human sperm" is out. Authors highlighted that the...

Oct 1, 2020

New paper

Our new paper from the RUNaway project is out! Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the...

Sep 23, 2020

Our research

And our most recent papers are out! We would like to congratulate all the authors who have been part of to this success by publishing...

Aug 3, 2020

"iBiMED: DID YOU KNOW?" interview

Professor Margarida Fardilha presented the Fardilha's lab work and investigation in male infertility and the cell signal pathways in an...

Jul 3, 2020

Investigation of spectroscopic and proteomic alterations underlying prostate carcinogenesis

Congratulations to all the authors, in special to authors from our team Juliana Felgueiras, Joana Vieira Silva and Margarida Fardilha!...

Jun 27, 2020

Tissue-Specific Cell Signalling book

We have the pleasure to announce the most recent book Tissue-Specific Cell Signalling edited by Joana Vieira Silva, Maria João Freitas...

Feb 10, 2020

The mammalian two-hybrid system as a powerful tool for high-throughput drug screening

Our latest article in Drug Discovery Today "The mammalian two-hybrid system as a powerful tool for high-throughput drug screening" has...

Nov 8, 2019

First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa

Our most recent published work by Joana Santiago, Joana Vieira Silva and Margarida Fardilha. Find more in: https://www.mdpi.com/1422-0067...

Oct 25, 2019

An efficient synthetic access to new uracil-alditols bearing a porphyrin unit and biological assessm

A new paper as been published with the participation of Fardilha's Laboratory. Congratulations to all the authors, specially to Juliana...

Oct 25, 2019

High-intensity, high-volume exercise in addition to school exercise classes reduces endothelial prog

The most recent published article from Fardilha's lab. The paper aimed to assess the effect of high intensity, high-volume swimming in...

Aug 22, 2019

New PhD grant

Fardilha's lab has a new PhD student. Congratulations to Bárbara Matos for the successful FCT application grant this year.

Jul 5, 2019

PO CH: Successful stories

The PhD student from our laboratory, Joana Santiago, participates in the 5th Informative flyer from PO CH (Programa Operacional Capital...

Jun 26, 2019

mTOR Signaling Pathway Regulates Sperm Quality in Older Men

The most recent published article from Fardilha's lab. The article is the first "to associate the mTOR signaling pathway with the age...

Jun 25, 2019

Europhosphatase: From Molecular Mechanisms to System-wide Responses

Margarida Fardilha has participate in the Europhosphatase: From Molecular Mechanisms to System-wide Responses 2019, a FEBS advanced...

Mar 25, 2019

Sulfate-based lipids: analysis of healthy human fluids and cell extracts

A new paper as been published with the participation of Fardilha's Laboratory. Congratulations to all the authors, specially to Joana...

Feb 19, 2019

Investigadores do iBiMED/UA estudam obstáculos à terapia em cancros da mama e próstata

Today, the paper "Contribution of the unfolded protein response to breast and prostate tissue homeostasis and its significance to cancer...

Feb 11, 2019

Contribution of the unfolded protein response to breast and prostate tissue homeostasis and its sign

The most recent published article from Fardilha's lab. Congrats to the authors from our team, Inês Direito and Margarida Fadilha!

Oct 24, 2018

The deletion of the protein phosphatase-1 regulator NIPP1 in testis causes hyperphosphorylation and

Our most recent published work. Congratulations to all the authors, specially to Mónica Ferreira and Margarida Fardilha. Read more:...

Aug 20, 2018

New PhD Grants

Fardilha's lab has 3 new PhD students. Congratulations to Joana Santiago, Daniela Patrício and Tânia Lima for the successful applications.

May 4, 2018

X Biochemistry Day@UA 2018

Bárbara Matos, participated on X Biochemistry Day with a poster publication, titled “Unraveling the effect of exercise training in testis...

Apr 23, 2018

Testicular aging: an overview of ultrastructural, cellular and molecular alterations

Our most recent work published by Joana Santiago, Joana Vieira Silva, Marco Alves, Pedro Oliveira and Margarida Fardilha. This paper...

Mar 17, 2018

Habilittation proofs of Margarida Fardilha

Margarida Fardilha is the new Assistant Professor with Habilittation of the Department of Medical Sciences. In the last 15th and 16th...

Feb 19, 2018

From protein structure to biological function through interactomics: an integrated view, 2nd edition

From protein structure to biological function through interactomics: an integrated view, 2nd edition, 5-9 February, Cantanhede, Portugal...

Feb 8, 2018

I NoTeS Congress – NOVEL THERAPEUTIC STRATEGIES FOR NONCOMMUNICABLE DISEASES

Faculty of Medicine - University of Porto, 22-23 June 2018 The I NoTeS Congress will constitute a discussion forum based on the most...

Jan 30, 2018

Workshop “Everything you want to know about the Li-COR Odyssey system” (5th of February 2018)

The aim of this workshop is to introduce or re-introduce the basic principles of obtaining and analyzing data from the LI-COR Odyssey...

Jan 29, 2018

Workshop “Application of bioinformatics tools to data analysis in Systems Medicine”

Date: March 7th 2018 Venue: Department of Medical Sciences, University of Aveiro, Portugal Overview: After the outburst of omics...

Jan 17, 2018

Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid scree

Our most recent work published. by Juliana Felgueiras, Joana Vieira Silva and Margarida Fardilha Congratulations to all authors. Read...

Jan 15, 2018

Maria João Freitas' PhD defense

Maria João Freitas successfully defended her PhD thesis entitled "Addressing sperm motility regulation by specific PPP1 inhibitors" in...

Oct 15, 2017

TECHDAYS 2017

Between 12-14 October, the Parque de Exposições of Aveiro was once again the home of Techdays, the event that started in 2015, and now,...

Oct 1, 2017

Workshop “Animal Models of Disease” (25th of October 2017)

The aim of this workshop is to demonstrate the animal models used in the clinic research. The workshop will consist of several talks...

Mar 17, 2017

A UA explica... estamos a ficar inférteis?

O sonho de ser pai ou mãe para cerca de 15 a 20 por cento dos casais férteis portugueses não passa disso mesmo: de um sonho. Porquê?...

Nov 4, 2016

Stop ao espermatozoide. Estudo admite pílula masculina sem efeitos secundários

A Investigação do Laboratório de Margarida Fardilha em destaque na rádio TSF. https://www.tsf.pt/sociedade/saude/interior/stop-ao-esperma...

Oct 28, 2016

VISÃO: Três investigadoras portuguesas são decisivas para a criação da pílula masculina

O Laboratório de Margarida Fardilha em destaque na revista VISÃO. http://visao.sapo.pt/actualidade/sociedade/2016-10-28-Tres-investigador...

Jul 8, 2016

Joana Vieira's PhD defense

Joana Vieira successfully defended her PhD thesis entitled "Sperm specific proteins and protein complexes as target for pharmaceutical...

May 14, 2014

Qualidade do sémen diminui com o aumento do consumo de álcool nas semanas académicas

A investigação do Laboratório de Margarida Fardilha permite concluir que a qualidade do sémen dos estudantes universitários diminui...

May 9, 2014

Semanas académicas dão cabo do sémen dos rapazes

Notícia publicada no site da TVI24. http://www.tvi24.iol.pt/tecnologia/alcool/semanas-academicas-dao-cabo-do-semen-dos-rapazes

Oct 24, 2012

Sara Esteves' PhD defense

May 4, 2012

"Para o frasco"

Diminuição de mais de 20 por cento na concentração dos espermatozoides e alterações em cerca de 15 por cento na morfologia destas células...